<div dir="ltr">Hello everybody,<div>Maybe some of you could be interested.</div><div>Diane<br><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">---------- Forwarded message ---------<br>De : <span dir="ltr"><<a href="mailto:evoldir@evol.biology.mcmaster.ca">evoldir@evol.biology.mcmaster.ca</a>></span><br>Date: mar. 14 mai 2019 à 08:12<br>Subject: Graduate position: Mainz_Germany.3.SocialInsectEvolution<br>To: <<a href="mailto:bigot.diane@gmail.com">bigot.diane@gmail.com</a>><br></div><br><br><br>
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3 PhD positions in evolutionary biology of social insects at the Johannes<br>
Gutenberg University of Mainz, Germany The Institute of Organismic and<br>
Molecular Evolution is seeking candidates for 3 PhD positions (starting<br>
October 1st 2019) to study the molecular regulation of ant social life<br>
within the Research Training Group GenEvo.<br>
<br>
Position 1 – Molecular regulation of reproduction in insect societies<br>
(co-supervised by Romain Libbrecht and René Ketting). The main feature<br>
of social insects is the reproductive division of labour, whereby queens<br>
monopolize reproduction while sterile workers perform other tasks to<br>
maintain the colony. Investigating the molecular mechanisms regulating<br>
reproduction and division of labour in ants is necessary to understand<br>
the evolution and ecological success of insect societies. The clonal<br>
raider ant O. biroi has emerged as a powerful study system to investigate<br>
gene regulatory processes and the molecular regulation of reproduction<br>
(Chandra et al. 2018, Libbrecht et al. 2016, Libbrecht et al. 2018). This<br>
project will identify putative gene regulatory mechanisms associated<br>
with reproduction, and investigate the functional link between social<br>
cues (presence of larvae), regulatory mechanisms, gene expression, and<br>
reproduction. It will thus shed light on the regulation and evolution<br>
of reproductive division of labour in insect societies, as well as on<br>
how gene regulation can translate social cues into physiological changes.<br>
<br>
Position 2 – Gene regulation and division of labour (co-supervised by<br>
Susanne Foitzik, Peter Baumann, Susanne Gerber). Social insect workers<br>
specialise in specific tasks and this division of labour contributes<br>
to the ecological success of insect societies. Task specialisation is<br>
mostly neither genetically determined nor rigid, but changes with age<br>
and colony needs. Typically, young workers takeover brood care, whereas<br>
older workers focus on risky tasks. The expression of behavioural genes<br>
shifts with the tasks of workers and histone acetylation can regulate<br>
task-specific gene expression (Simola et al. 2016). Our preliminary<br>
work revealed division of labour, the expression and functions of<br>
task-specific genes (Feldmeyer et al. 2014; Kohlmeier et al. 2018; 2019),<br>
and the importance of histone acetylation for their expression in the ant<br>
Temnothorax longispinosus. This projects aims to understand how different<br>
regulatory processes respond to external cues, the expression of which<br>
genes they alter and how fast they can change gene expression. It will<br>
thus give insights into the molecular regulation of worker division of<br>
labour in social insects.<br>
<br>
Position 3 – Parasite interference with gene regulation of a<br>
social host (co-supervised by Susanne Foitzik, Peter Baumann, Falk<br>
Butter). Parasites with complex life cycles often manipulate the<br>
behaviour of their intermediate hosts to increase transmission to the<br>
definite host and we hypothesise that they do so by interfering with<br>
host gene regulation. Infection of Temnothorax nylanderi ant larvae<br>
with the parasitic cestode Anomotaenia brevis strongly alters the adult<br>
phenotype. Parasitized workers exhibit altered behaviour, morphology,<br>
chemical profile and a lifespan extension (Scharf et al. 2012, Beros et<br>
al. 2015), and these changes are linked to transcriptomic alterations<br>
(Feldmeyer et al. 2016). The cestode, residing in its cysticercoid stage<br>
in the ants’ gaster is transcriptionally active and releases many<br>
proteins into the host. The aim of this project is to demonstrate that<br>
parasite-induced changes in host phenotype are actively promoted by the<br>
parasite. We therefore will study how the cestode parasite interferes<br>
with the hosts’ gene regulation, which gene-regulatory mechanisms<br>
are utilised and whether these alterations are permanent or have to be<br>
actively maintained. This project will reveal genetic and epigenetic<br>
underpinnings of behaviour and longevity in social insects and will<br>
uncover the mechanisms of across-species interference in gene regulation.<br>
<br>
We are looking for highly motivated students with a Master degree<br>
(or equivalent) in biology, good English skills, and a keen interest in<br>
evolutionary biology. Previous experience with social insects, statistics<br>
and bioinformatics is advantageous, but not required. Successful<br>
applicants will join an international, interactive, dynamic and<br>
English-speaking scientific environment in a brand new building<br>
with access to state-of-the-art, newly equipped laboratories and<br>
climate-controlled rooms. The JGU of Mainz hosts many excellent scientific<br>
institutions, and Mainz is a historic city located on the Rhine River<br>
with a large student population and a rich social and cultural life.<br>
<br>
Interested candidates should apply to the IPP summer call 2019. They will<br>
have to register before May 22nd 2019 and complete their application<br>
before May 27th 2019. Informal enquiries should be sent to Dr. Romain<br>
Libbrecht (<a href="mailto:romain.libbrecht@uni-mainz.de" target="_blank">romain.libbrecht@uni-mainz.de</a>) for position 1 and Dr. Susanne<br>
Foitzik (<a href="mailto:foitzik@uni-mainz.de" target="_blank">foitzik@uni-mainz.de</a>) for positions 2 and 3. The starting<br>
date for all three positions is October 1st 2019. The Johannes<br>
Gutenberg University of Mainz is interested in increasing the number<br>
of women in science. Applications from women are therefore strongly<br>
encouraged. Similarly, qualified candidates with disabilities will<br>
be preferred.<br>
<br>
GenEvo: <a href="https://www.imb.de/about-imb/joint-research-initiatives/genevo/" rel="noreferrer" target="_blank">https://www.imb.de/about-imb/joint-research-initiatives/genevo/</a><br>
IPP summer call 2019:<br>
<a href="https://www.imb.de/students-postdocs/international-phd-programme/apply-to-ipp/projects-offered/" rel="noreferrer" target="_blank">https://www.imb.de/students-postdocs/international-phd-programme/apply-to-ipp/projects-offered/</a><br>
<br>
<br>
<br>
<br>
Dr. Romain Libbrecht<br>
Assistant Professor / Junior Group Leader<br>
Institute of Organismic and Molecular Evolution<br>
Johannes Gutenberg University<br>
Mainz, Germany<br>
<br>
+49 6131 3927852<br>
<br>
<a href="https://www.blogs.uni-mainz.de/fb10-evolutionary-biology/research-groups/group-libbrecht/" rel="noreferrer" target="_blank">https://www.blogs.uni-mainz.de/fb10-evolutionary-biology/research-groups/group-libbrecht/</a><br>
<br>
<br>
Romain Libbrecht <<a href="mailto:romain.libbrecht@gmail.com" target="_blank">romain.libbrecht@gmail.com</a>><br>
<br>
</div><br clear="all"><div><br></div>-- <br><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><span><font color="#888888">PhD Diane BIGOT<br><a href="mailto:bigot.diane@gmail.com" target="_blank">bigot.diane@gmail.com</a><br>Post-doctoral researcher<br></font></span></div><div><span><font color="#888888">Martin-Luther-Universität Halle-Wittenberg<br></font></span></div><div dir="ltr"><span><font color="#888888">Institute of Biology/Zoology<br>Hoher Weg 8, 06120 Halle (Saale), Germany</font></span><br><span></span></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div>